Substrates for peptidase C14.034: metacaspase-9 (Arabidopsis-type)

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
Boc-Gly-Arg-Arg-NHMec			Boc-Gly-Arg-Arg+NHMec	S		Boc	Gly	Arg	Arg	AMC	-	-	-	Vercammen et al., 2004
Boc-Gly-Lys-Arg-NHMec			Boc-Gly-Lys-Arg+NHMec	S		Boc	Gly	Lys	Arg	AMC	-	-	-	Vercammen et al., 2004
D-Val-Lys-Lys-Arg-NHMec			D-Val-Lys-Lys-Arg+NHMec	S	NT	Val	Lys	Lys	Arg	AMC	-	-	-	Vercammen et al., 2004
metacaspase 9 precursor	Q9FYE1	1-325	peptide-Arg183+Ala-peptide	P		Ile	Thr	Ser	Arg	Ala	Leu	Pro	Phe	Vercammen et al., 2004	16256
Z-Phe-Arg-NHMec			Z-Phe-Arg+NHMec	S		-	Z	Phe	Arg	AMC	-	-	-	Vercammen et al., 2004