Substrates for peptidase C13.005: glycosylphosphatidylinositol:protein transamidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
1,3-beta-glucanosyltransferase GAS1 P22146 23-559 peptide-Asn528+Ala-peptide P NT Ser Lys Lys Asn Ala Ala Thr Asn Popolo et al., 2008
1,3-beta-glucanosyltransferase GAS1 P23151 23-559 peptide-Asn528+Ala-peptide P NT Ser Lys Lys Asn Ala Ala Thr Asn Popolo et al., 2008
5'-nucleotidase P21589 27-574 peptide-Ser549+Thr-peptide P NT Ile Lys Phe Ser Thr Gly Ser His Misumi et al., 1990
5'-nucleotidase P21588 29-576 peptide-Ser551+Ala-peptide P NT Ile Lys Phe Ser Ala Ala Ser His Ogata et al., 1990
Acetylcholinesterase isoform T P04058-2 22-596 peptide-Arg564+Gln-peptide P NT Glu Ala Glu Arg Gln Trp Lys Thr McPhee-Quigley et al., 1986
Alkaline phosphatase, placental type P05187 23-535 peptide-Asp506+Ala-peptide P NT Gly Thr Thr Asp Ala Ala His Pro Henthorn et al., 1986
Alpha-agglutinin P20840 20-650 peptide-Gly627+Lys-peptide N NT Thr Tyr Glu Gly Lys Ala Ser Ile
Carbonic anhydrase 4 P22748 19-312 peptide-Ser284+Gly-peptide P NT Val Ile Lys Ser Gly Ala Pro Gly Okuyama et al., 1995
Carboxypeptidase M P14384 18-443 peptide-Ser423+Ala-peptide P NT Pro Asp His Ser Ala Ala Thr Lys Tan et al., 2003
CD59 glycoprotein P13987 26-128 peptide-Asn102+Gly-peptide P NT Gln Leu Glu Asn Gly Gly Thr Ser Acosta et al., 2000
cell-cell adhesion glycoprotein 64 Q52085 20-320 peptide-Ser298+Ser-peptide P NT Asn Val Cys Ser Ser Ala Thr Thr Manabe et al., 1994
Complement decay-accelerating factor P08174 35-440 peptide-Ser353+Gly-peptide P NT Gly Thr Thr Ser Gly Thr Thr Arg Storry et al., 2003
Complement decay-accelerating factor P09679 35-440 peptide-Ser353+Gly-peptide P NT Gly Thr Thr Ser Gly Thr Thr Arg Storry et al., 2003
Dipeptidase 1 P16444 17-411 peptide-Ser385+Gly-peptide P NT Gly Tyr Ser Ser Gly Ala Ser Ser Sjoeblom et al., 2006
Folate receptor alpha P15328 25-257 peptide-Ser234+Gly-peptide P NT Ala Ala Met Ser Gly Ala Gly Pro Picariello et al., 2008
Leishmanolysin P08148 40-602 peptide-Asn577+Thr-peptide P NT Asp Gly Gly Asn Thr Ala Ala Gly McGwire & Chang, 1996
Leishmanolysin P15906 40-602 peptide-Asn577+Thr-peptide P NT Asp Gly Gly Asn Thr Ala Ala Gly McGwire & Chang, 1996
Major prion protein P04273 23-254 peptide-Ile231+Ser-peptide P NT Ile Leu Leu Ile Ser Phe Leu Ile Turk et al., 1988
Procyclic form-specific polypeptide A-beta P09791 28-129 peptide-Gly107+Ala-peptide P NT Pro Glu Pro Gly Ala Ala Thr Leu Clayton & Mowatt, 1989