Substrates for peptidase C09.001: sindbis virus-type nsP2 peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference	CutDB
non-structural polyprotein	P03317	1-2512	peptide-Ala540+Ala-peptide	P	Asp	Ile	Gly	Ala	Ala	Leu	Val	Glu		16209
non-structural polyprotein	P03317	1-2512	peptide-Ala1347+Ala-peptide	P	Gly	Val	Gly	Ala	Ala	Pro	Ser	Tyr		16208
non-structural polyprotein	P03317	1-2512	peptide-Tyr1896+Leu-peptide	P	Arg	Thr	Glu	Tyr	Leu	Thr	Gly	Val		16210
non-structural polyprotein	P08411	1-2432	peptide-Ala537+Gly-peptide	P	His	Ala	Gly	Ala	Gly	Val	Val	Glu	Vasiljeva et al., 2003
non-structural polyprotein	P08411	1-2432	peptide-Ala1337+Pro-peptide	P	Ala	Gly	Cys	Ala	Pro	Ser	Tyr	Arg	Vasiljeva et al., 2003
non-structural polyprotein	P08411	1-2432	peptide-Tyr1819+Ile-peptide	P	Ala	Gly	Ala	Tyr	Ile	Phe	Ser	Ser	Vasiljeva et al., 2003