Substrates for peptidase A08.001: signal peptidase II

Summary Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate Uniprot Residue range Cleavage Site Cleavage type Evidence P4 P3 P2 P1 P1' P2' P3' P4' Reference CutDB MERNUM
consensus bond -Leu-Ala/Ser-Gly/Ala+Cys N NPe Leu Ala Gly Cys CPe - - Sankaran, 2004
consensus bond -Leu-Ala/Ser-Gly/Ala+Cys N NPe Leu Ser Gly Cys CPe - - Sankaran, 2004
consensus bond -Leu-Ala/Ser-Gly/Ala+Cys N NPe Leu Ala Ala Cys CPe - - Sankaran, 2004
consensus bond -Leu-Ala/Ser-Gly/Ala+Cys N NPe Leu Ser Ala Cys CPe - - Sankaran, 2004
major outer membrane lipoprotein precursor P69776 1-78 peptide-Leu20+Cys-peptide P Leu Leu Ala Gly Cys Ser Ser Asn 16035