Substrates for peptidase A01.051: pepsin F

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are thought to be pathologically relevant are indicated by D. Peptide and protein substrates that are not physiologically relevant are indicated by N. Synthetic substrates are indicated by S. Click on the symbol to show only physiological, non-physiological or synthetic substrates, or here to display all substrates. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a protein substrate, click on the UniProt Accession.

Substrate	Uniprot	Residue range	Cleavage Site	Cleavage type	Evidence	P4	P3	P2	P1	P1'	P2'	P3'	P4'	Reference
(7-methoxycoumarin-4-yl) acetyl-Gly-Lys-Pro-Ile-Leu-Phe-Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2			(7-methoxycoumarin-4-yl) acetyl-Gly-Lys-Pro-Ile-Leu-Phe+Phe-Arg-Leu-Lys(Dnp)-D-Arg-NH2	S		Pro	Ile	Leu	Phe	Phe	Arg	Leu	Lys	Telugu & Green, 2008
Pregnancy-associated glycoprotein	Q28389	16-388	Peptide-Leu37+Lys-Peptide	P	NT	Lys	Asp	Met	Leu	Lys	Glu	Tyr	Leu	Green et al., 1999
Pregnancy-associated glycoprotein	Q28389	16-388	Peptide-Leu48+Thr-Peptide	P	NT	Pro	Phe	Arg	Leu	Thr	His	Lys	Leu	Green et al., 1999