Structure for peptidase S62.001: influenza A PA peptidase

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature

TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
influenza A virus
crystal structure of pa-pb1 complex form influenza virus rna polymerase	2.30 Å	2ZNL	2ZNL	2ZNL	2ZNL	2ZNL	2ZNL
RNA polymerase subunit	2.90 Å	3CM8	3CM8	3CM8	3CM8	3CM8	3CM8	He et al., 2008
N-terminal, non-peptidase domain	2.20 Å	3EBJ	3EBJ	3EBJ	3EBJ	3EBJ	3EBJ	Yuan et al., 2009
the crystal structure of avian influenza virus pa_n in complex with ump	1.90 Å	3HW3	3HW3	3HW3	3HW3	3HW3	3HW3
crystal structure of avian influenza a virus in complex with tmp	1.90 Å	3HW4	3HW4	3HW4	3HW4	3HW4	3HW4
crystal structure of avian influenza virus pa_n in complex with amp	1.81 Å	3HW5	3HW5	3HW5	3HW5	3HW5	3HW5
crystal structure of avian influenza virus pa_n in complex with mn	2.50 Å	3HW6	3HW6	3HW6	3HW6	3HW6	3HW6
electron cryo-microscopy of an rna polymerase	4.30 Å	3J9B	3J9B	3J9B	3J9B	3J9B	3J9B
crystal structure of avian influenza virus pan apo	2.05 Å	4E5E	4E5E	4E5E	4E5E	4E5E	4E5E
crystal structure of avian influenza virus pan bound to compound 1	2.39 Å	4E5F	4E5F	4E5F	4E5F	4E5F	4E5F
crystal structure of avian influenza virus pan bound to compound 2	2.65 Å	4E5G	4E5G	4E5G	4E5G	4E5G	4E5G
crystal structure of avian influenza virus pan bound to compound 3	2.16 Å	4E5H	4E5H	4E5H	4E5H	4E5H	4E5H
crystal structure of avian influenza virus pan bound to compound 4	2.94 Å	4E5I	4E5I	4E5I	4E5I	4E5I	4E5I
crystal structure of avian influenza virus pan bound to compound 5	2.35 Å	4E5J	4E5J	4E5J	4E5J	4E5J	4E5J
crystal structure of avian influenza virus pan bound to compound 6	2.47 Å	4E5L	4E5L	4E5L	4E5L	4E5L	4E5L
structure of polymerase acid protein (pa) from influenzavirus a influenza a virus a, wilson-smith/1933 (h1n1)	1.90 Å	4IUJ	4IUJ	4IUJ	4IUJ	4IUJ	4IUJ
2-(4-(1h-tetrazol-5-yl)phenyl)-5-hydroxypyrimidin-4(3h)-one bound to influenza 2009 h1n1 endonuclease	1.80 Å	4W9S	4W9S	4W9S	4W9S	4W9S	4W9S
phenolic acid derivative bound to influenza strain h1n1 polymerase subunit pa endonuclease	1.91 Å	4YYL	4YYL	4YYL	4YYL	4YYL	4YYL
endonuclease inhibitor bound to influenza strain h1n1 polymerase acidic subunit n-terminal region with expelling one of the metal ionsin the active site	2.50 Å	4ZHZ	4ZHZ	4ZHZ	4ZHZ	4ZHZ	4ZHZ
endonuclease inhibitor bound to influenza strain h1n1 polymerase acidic subunit n-terminal region without a chelation to the metal ions in the active site	1.80 Å	4ZI0	4ZI0	4ZI0	4ZI0	4ZI0	4ZI0
apo form of influenza strain h1n1 polymerase acidic subunit n-terminal region	1.80 Å	4ZQQ	4ZQQ	4ZQQ	4ZQQ	4ZQQ	4ZQQ
endonuclease inhibitor 1 bound to influenza strain h1n1 polymerase acidic subunit n-terminal region at ph 7.0	2.51 Å	5FDD	5FDD	5FDD	5FDD	5FDD	5FDD
endonuclease inhibitor 3 bound to influenza strain h1n1 polymerase acidic subunit n-terminal region at ph 7.0	2.10 Å	5FDG	5FDG	5FDG	5FDG	5FDG	5FDG
endonuclease inhibitor 2 bound to influenza strain h1n1 polymerase acidic subunit n-terminal region at ph 7.0	2.15 Å	5I13	5I13	5I13	5I13	5I13	5I13
crystal structure of polymerase acid protein (pa) from influenza a virus, wilson-smith/1933 (h1n1) bound to fragment hit ebsi-747 1-(4- chlorophenyl)-1h-imidazole	2.20 Å	5IEQ	5IEQ	5IEQ	5IEQ	5IEQ	5IEQ
crystal structure of polymerase acid protein (pa) from influenza a virus, wilson-smith/1933 (h1n1) bound to fragment hit ebsi-576 (5,6- dichloro-1h-1,3-benzodiazol-2-yl)methanol	2.35 Å	5IF2	5IF2	5IF2	5IF2	5IF2	5IF2
crystal structure of polymerase acid protein (pa) from influenza a virus, wilson-smith/1933 (h1n1) bound to ebsi-39 (2,3- dichlorophenyl)methanol	2.25 Å	5IF5	5IF5	5IF5	5IF5	5IF5	5IF5
crystal structure of polymerase acid protein (pa) from influenza a virus, wilson-smith/1933 (h1n1) bound to fragment hit ebsi-279 n-[(4-chlorophenyl)methyl]-1-methyl-1h-pyrazolo[3,4-d]pyrimidin-4-amine	2.65 Å	5IF7	5IF7	5IF7	5IF7	5IF7	5IF7
crystal structure of polymerase acid protein (pa) from influenza a virus, wilson-smith/1933 (h1n1) bound to fragment hit ebsi-2643 5- [(4-chlorophenyl)methyl]-1,3,4-oxadiazol-2-amine	2.30 Å	5IF8	5IF8	5IF8	5IF8	5IF8	5IF8
crystal structure of polymerase acid protein (pa) from influenza a virus, wilson-smith/1933 (h1n1) bound to follow on fragment ebsi-47195-chloro-2-(1h-imidazol-1-yl)aniline	2.45 Å	5IFB	5IFB	5IFB	5IFB	5IFB	5IFB
crystal structure of polymerase acid protein (pa) from influenza a virus, wilson-smith/1933 (h1n1) bound to follow on fragment ebsi-47201-(4-bromophenyl)-1h-imidazole	2.65 Å	5IFC	5IFC	5IFC	5IFC	5IFC	5IFC
crystal structure of polymerase acid protein (pa) from influenza a virus, wilson-smith/1933 (h1n1) bound to follow on fragment ebsi-47211-(4-fluorophenyl)-1h-imidazole	2.65 Å	5IFD	5IFD	5IFD	5IFD	5IFD	5IFD
apo form of influenza strain h1n1 polymerase acidic subunit n-terminalregion crystallized with potassium sodium tartrate	1.75 Å	5JHT	5JHT	5JHT	5JHT	5JHT	5JHT
apo form of influenza strain h1n1 polymerase acidic subunit n-terminalregion crystallized with polyethylene glycol 8000	2.75 Å	5JHV	5JHV	5JHV	5JHV	5JHV	5JHV
crystal structure of polymerase acid protein (pa) from influenza a virus, wilson-smith/1933 (h1n1) bound to follow on fragment ebsi-47234-(5-chlorothiophen-2-yl)-1h-pyrazole	2.45 Å	5V0U	5V0U	5V0U	5V0U	5V0U	5V0U
crystal structure of polymerase acid protein (pa) from influenza a virus, wilson-smith/1933 (h1n1) bound to fragment hit bsi-70565 1-1-[4-fluorophenyl)methyl]-2-methyl-1h-imidazol-4-ylethan-1-one	2.45 Å	6CFP	6CFP	6CFP	6CFP	6CFP	6CFP