Structure for peptidase M49.001: dipeptidyl-peptidase III

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

 

PDB Organism Resolution Comment
3FVY_A Homo sapiens 1.90 Å mature
The catalytic zinc atom is shown as a light grey CPK sphere. The zinc ligands are shown in ball-and-stick representation: His450 and His455 in purple and Glu508 in blue. The catalytic Glu451 is shown in blue ball-and-stick representation. The structural magnesium atoms are shown as green CPK spheres.
This browser does not have a Java Plug-in.
Get the latest Java Plug-in here.
Show surface
TERTIARY STRUCTURE DATA
Comment Resolution PDB PDBe SCOP CATH PDBSum Proteopedia Reference
Homo sapiens
mature  peptidase 1.90 Å 3FVY 3FVY 3FVY 3FVY 3FVY 3FVY
mature  peptidase 2.40 Å 3T6B 3T6B 3T6B 3T6B 3T6B 3T6B Bezerra et al., 2012
mature  peptidase 2.98 Å 3T6J 3T6J 3T6J 3T6J 3T6J 3T6J Bezerra et al., 2012
complex with angiotensin-ii 2.40 Å 5E2Q 5E2Q 5E2Q 5E2Q 5E2Q 5E2Q
complex with met-enkephalin 1.84 Å 5E33 5E33 5E33 5E33 5E33 5E33
complex with opioid peptide leu-enkephalin 2.05 Å 5E3A 5E3A 5E3A 5E3A 5E3A 5E3A
complex with hemorphin like opioid peptide ivypw 2.77 Å 5E3C 5E3C 5E3C 5E3C 5E3C 5E3C
structure of ligand free human dpp3 in closed form. 2.74 Å 5EGY 5EGY 5EGY 5EGY 5EGY 5EGY
complex with endomorphin-2. 2.38 Å 5EHH 5EHH 5EHH 5EHH 5EHH 5EHH