Structure for peptidase M03.002: neurolysin
 
| PDB | Organism | Resolution | Comment |
|---|---|---|---|
| 1I1I_P | Rattus norvegicus | 2.30 Å | mature |
| The catalytic and structural zinc ions are shown as light grey CPK spheres. The zinc ligands are shown in ball-and-stick representation: His497 and His501 in purple and Glu526 in dark blue. The catalytic Glu498 is shown in ball-and-stick representation in blue. | |||
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| TERTIARY STRUCTURE DATA | ||||||||
|---|---|---|---|---|---|---|---|---|
| Comment | Resolution | PDB | PDBe | SCOP | CATH | PDBSum | Proteopedia | Reference |
| Homo sapiens | ||||||||
| Glu475Gln mutant; complex with neurotensin peptide products | 2.70 Å | 5LUZ | 5LUZ | 5LUZ | 5LUZ | 5LUZ | 5LUZ | |
| Glu475Gln mutant; complex with amyloid-beta 35-40 peptide product | 2.70 Å | 5LV0 | 5LV0 | 5LV0 | 5LV0 | 5LV0 | 5LV0 | |
| Rattus norvegicus | ||||||||
| mature peptidase | 2.30 Å | 1I1I | 1I1I | 1I1I | 1I1I | 1I1I | 1I1I | Brown et al., 2001 |
| engineered with thimet oligopeptidase specificity for neurotensin cleavage site | 2.20 Å | 2O3E | 2O3E | 2O3E | 2O3E | 2O3E | 2O3E | Lim et al., 2007 |
| mature peptidase | 2.80 Å | 4FXY | 4FXY | 4FXY | 4FXY | 4FXY | 4FXY | Hines et al., 2014 |


