Structure for peptidase C13.004: legumain, animal-type

PDB	Organism	Resolution	Comment
4AW9	Homo sapiens	2.20 Å	complex with Ac-Tyr-Val-Ala-Asp-chloromethylketone
Catalytic residues are shown in ball-and-stick representation: His148 in purple and Cys189 in yellow. Carbohydrates are shown as CPK spheres in yellow. Ac-Tyr-Val-Ala-Asp-chloromethylketone is shown in grey in ball-and-stick representation.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Cricetulus griseus
mature peptidase	1.85 Å	4D3X	4D3X	4D3X	4D3X	4D3X	4D3X
precursor	2.40 Å	4D3Y	4D3Y	4D3Y	4D3Y	4D3Y	4D3Y
precursor; trigonal space group	2.30 Å	4D3Z	4D3Z	4D3Z	4D3Z	4D3Z	4D3Z
Homo sapiens
complex with Ac-Tyr-Val-Ala-Asp-chloromethylketone	2.20 Å	4AW9	4AW9	4AW9	4AW9	4AW9	4AW9	Dall & Brandstetter, 2013
complex with Ac-Tyr-Val-Ala-Asp-chloromethylketone at pH 5.0	2.50 Å	4AWA	4AWA	4AWA	4AWA	4AWA	4AWA	Dall & Brandstetter, 2013
complex with Z-Ala-Ala-AzaAsn-chloromethylketone	2.70 Å	4AWB	4AWB	4AWB	4AWB	4AWB	4AWB	Dall & Brandstetter, 2013
precursor	3.90 Å	4FGU	4FGU	4FGU	4FGU	4FGU	4FGU	Dall & Brandstetter, 2013
oxidised form in complex with cystatin E/M	1.87 Å	4N6N	4N6N	4N6N	4N6N	4N6N	4N6N	Dall et al., 2015
complex with cystatin E/M	1.80 Å	4N6O	4N6O	4N6O	4N6O	4N6O	4N6O	Dall et al., 2015
YVAD-CMK bound form; complex with compound 11b	1.95 Å	5LU8	5LU8	5LU8	5LU8	5LU8	5LU8
YVAD-CMK bound form; complex with compound 11	2.27 Å	5LU9	5LU9	5LU9	5LU9	5LU9	5LU9
complex with compound 11b	2.00 Å	5LUA	5LUA	5LUA	5LUA	5LUA	5LUA
complex with compound 11	2.10 Å	5LUB	5LUB	5LUB	5LUB	5LUB	5LUB
Mus musculus
activated at pH 3.5	2.80 Å	4NOJ	4NOJ	4NOJ	4NOJ	4NOJ	4NOJ	Zhao et al., 2014
precxursor at pH 7.5	2.50 Å	4NOK	4NOK	4NOK	4NOK	4NOK	4NOK	Zhao et al., 2014
Asp223Ala mutant; precursor at pH 7.5	2.70 Å	4NOL	4NOL	4NOL	4NOL	4NOL	4NOL	Zhao et al., 2014
activated at pH 4.5	2.01 Å	4NOM	4NOM	4NOM	4NOM	4NOM	4NOM	Zhao et al., 2014