Structure for peptidase C02.001: calpain-1

PDB	Organism	Resolution	Comment
2ARY	Homo sapiens	2.40 Å	catalytic domain only
Catalytic residues are shown in ball-and-stick representation: Gln109 and Asn296 in pink, Cys115 in yellow and His272 in purple.

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TERTIARY STRUCTURE DATA
Comment	Resolution	PDB	PDBe	SCOP	CATH	PDBSum	Proteopedia	Reference
Homo sapiens
complex with inhibitor Z-Leu-Leu-Tyr-CH2F	2.00 Å	1ZCM	1ZCM	1ZCM	1ZCM	1ZCM	1ZCM	Li et al., 2006
catalytic domain only	2.40 Å	2ARY	2ARY	2ARY	2ARY	2ARY	2ARY	Davis et al., 2007
Rattus norvegicus
catalytic domain only	2.07 Å	1KXR	1KXR	1KXR	1KXR	1KXR	1KXR	Moldoveanu et al., 2002
mature peptidase	2.80 Å	1QXP	1QXP	1QXP	1QXP	1QXP	1QXP	Pal et al., 2003
protease core; complex with leupeptin	1.80 Å	1TL9	1TL9	1TL9	1TL9	1TL9	1TL9	Moldoveanu et al., 2004
peptidase unit only; complex with E64	1.90 Å	1TLO	1TLO	1TLO	1TLO	1TLO	1TLO	Moldoveanu et al., 2004
calpain 1 proteolytic core;ncomplex with snj-1715, a cyclic hemiacetal-type inhibitor	2.25 Å	2G8E	2G8E	2G8E	2G8E	2G8E	2G8E	Cuerrier et al., 2006
proteolytic core; complex with snj-1945, a alpha-ketoamide-type inhibitor.	1.61 Å	2G8J	2G8J	2G8J	2G8J	2G8J	2G8J	Cuerrier et al., 2006
calpain 1 proteolytic core inactivated by wr18(s,s), an epoxysuccinyl-type inhibitor.	2.04 Å	2NQG	2NQG	2NQG	2NQG	2NQG	2NQG	Cuerrier et al., 2007
calpain 1 proteolytic core inactivated by wr13(r,r), an epoxysuccinyl-type inhibitor.	2.04 Å	2NQI	2NQI	2NQI	2NQI	2NQI	2NQI	Cuerrier et al., 2007
calpain 1 proteolytic core inactivated by zlak-3001, an alpha-ketoamide	1.80 Å	2R9C	2R9C	2R9C	2R9C	2R9C	2R9C	Qian et al., 2008
calpain 1 proteolytic core inactivated by zlak-3002, an alpha-ketoamide	1.60 Å	2R9F	2R9F	2R9F	2R9F	2R9F	2R9F	Qian et al., 2008