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Literature for peptidase C02.001: calpain-1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(Topics flags: S Structure, A Assay, T Target, P Specificity, K Knockout, E Expression, V Review, M Mutation, I Inhibitor, L Localization, U Therapeutic. To select only the references relevant to a single topic, click the link above. See explanation.)

    2025
  1. Chukai,Y., Furukawa,N., Kosegawa,O., Bai,L., Sugano,E., Fukuda,T., Tomita,H. and Ozaki,T.
    Mitochondrial calpain-1 truncates ATP synthase beta subunit
    Biochem Biophys Res Commun765, 151829-151829. PubMed  Europe PubMed DOI
  2. Horbach,N., Kalinka,M., Cwilichowska-Puslecka,N., Al Mamun,A., Mikolajczyk-Martinez,A., Turk,B., Snipas,S.J., Kasperkiewicz,P., Groborz,K.M. and Poreba,M.
    Visualization of calpain-1 activation during cell death and its role in GSDMD cleavage using chemical probes
    Cell Chem Biol PubMed  Europe PubMed DOI
  3. Najdek,C., Walle,P., Flaig,A., Ayral,A.M., Demiautte,F., Coulon,A., Buiche,V., Lambert,E., Amouyel,P., Gelle,C., Siedlecki-Wullich,D., Dumont,J., Kilinc,D., Eysert,F., Lambert,J.C. and Chapuis,J.
    Calpain and caspase regulate Abeta peptide production via cleavage of KINDLIN2 encoded by the AD-associated gene FERMT2
    Neurobiol Aging151, 117-125. PubMed  Europe PubMed DOI
  4. Shi,Y., Gu,W., Wei,Y., Li,S., Zhang,S., Jiang,Y., Chen,C., Liu,T., Shuai,L., Zhou,X. and Tang,F.
    Deficiency of Calpain-1 attenuates atherosclerotic plaque and calcification and improves vasomotor dysfunction in Apolipoprotein E knockout mice through inhibiting inflammation
    Biochem Biophys Res Commun749, 151369-151369. PubMed  Europe PubMed DOI
  5. Taylor,K.A., Elgheznawy,A., Adiyaman,R., Horn,T.L., Parkes,S., Hughes,C.E., McGuffin,L.J. and Gibbins,J.M.
    Inter-platelet communication driving thrombus formation is regulated by extracellular calpain-1 cleavage of connexin 62
    Haematologica PubMed  Europe PubMed DOI
    6. 2024
  6. Baudry,M. and Bi,X.
    Revisiting the calpain hypothesis of learning and memory 40 years later
    Front Mol Neurosci17, 1337850-1337850. PubMed  Europe PubMed DOI  V
  7. Biswal,L., Sahu,V.K., Sardoiwala,M.N., Karmakar,S. and Choudhury,S.R.
    Antibody conjugated targeted nanotherapy epigenetically inhibits calpain-mediated mitochondrial dysfunction to attenuate Parkinson's disease
    Carbohydr Polym346, 122575-122575. PubMed  Europe PubMed DOI
  8. Shu,J., Ma,X., Zou,J., Yuan,Z. and Yi,Z.
    Zika virus infection triggers caspase cleavage of STAT1
    Microbiol Spectr12, e0360923-e0360923. PubMed  Europe PubMed DOI
  9. Xie,X., Lan,Q., Zhao,J., Zhang,S., Liu,L., Zhang,Y., Xu,W., Shao,M., Peng,J., Xia,S., Zhu,Y., Zhang,K., Zhang,X., Zhang,R., Li,J., Dai,W., Ge,Z., Hu,S., Yu,C., Wang,J., Ma,D., Zheng,M., Yang,H., Xiao,G., Rao,Z., Lu,L., Zhang,L., Bai,F., Zhao,Y., Jiang,S. and Liu,H.
    Structure-based design of pan-coronavirus inhibitors targeting host cathepsin L and calpain-1
    Signal Transduct Target Ther9, 54-54. PubMed  Europe PubMed DOI  I
    10. 2023
  10. Ojima,K., Hata,S., Shinkai-Ouchi,F., Ono,Y. and Muroya,S.
    Calpain-3 not only proteolyzes calpain-1 and -2 but also is a substrate for calpain-1 and -2
    J Biochem174, 421-431. PubMed  Europe PubMed DOI
  11. Quinn,J.P., Ethier,E.C., Novielli,A., Malone,A., Ramirez,C.E., Salloum,L., Trombetta,B.A., Kivisakk,P., Bremang,M., Selzer,S., Fournier,M., Das,S., Xing,Y., Arnold,S.E. and Carlyle,B.C.
    Cerebrospinal Fluid and Brain Proteoforms of the Granin Neuropeptide Family in Alzheimer's Disease
    J Am Soc Mass Spectrom34, 649-667. PubMed  Europe PubMed DOI
    12. 2022
  12. Chen,Q., Thompson,J., Hu,Y. and Lesnefsky,E.J.
    The mitochondrial electron transport chain contributes to calpain 1 activation during ischemia-reperfusion
    Biochem Biophys Res Commun613, 127-132. PubMed  Europe PubMed DOI
    13. 2021
  13. Knopp,R.C., Jastaniah,A., Dubrovskyi,O., Gaisina,I., Tai,L. and Thatcher,G.R.J.
    Extending the Calpain-Cathepsin Hypothesis to the Neurovasculature: Protection of Brain Endothelial Cells and Mice from Neurotrauma
    ACS Pharmacol Transl Sci4, 372-385. PubMed  Europe PubMed DOI
  14. Wang,J., Ciampa,G., Zheng,D., Shi,Q., Chen,B., Abel,E.D., Peng,T., Hall,D.D. and Song,L.S.
    Calpain-2 specifically cleaves Junctophilin-2 at the same site as Calpain-1 but with less efficacy
    Biochem J478, 3539-3553. PubMed  Europe PubMed DOI
    15. 2020
  15. Asano,T., Nagayo,Y., Tsuda,S., Ito,A., Kobayashi,W., Fujita,K., Sato,K., Nishiguchi,K.M., Kunikata,H., Fujioka,H., Kamiya,M., Urano,Y. and Nakazawa,T.
    Companion Diagnosis for Retinal Neuroprotective Treatment by Real-Time Imaging of Calpain Activation Using a Novel Fluorescent Probe
    Bioconjug Chem31, 2241-2251. PubMed  Europe PubMed DOI  I
  16. Baliova,M. and Jursky,F.
    Phosphorylation of serine 157 protects the rat glycine transporter GlyT2 from calpain cleavage
    J Mol Neurosci PubMed  Europe PubMed DOI
  17. Chang,Y.S., Wu,S.Y., Stromer,M.H. and Chou,R.R.
    Calpain activation and proteolysis in postmortem goose muscles
    Anim Sci J91, e13423-e13423. PubMed  Europe PubMed DOI
  18. Dewitt,S. and Hallett,M.B.
    Calpain activation by Ca(2+) and its role in phagocytosis
    Adv Exp Med Biol1246, 129-151. PubMed  Europe PubMed DOI
  19. Ding,Z., Wei,Q., Zhang,C., Zhang,H. and Huang,F.
    Influence of oxidation on heat shock protein 27 translocation, caspase-3 and calpain activities and myofibrils degradation in postmortem beef muscles
    Food Chem340, 127914-127914. PubMed  Europe PubMed DOI
  20. Donkor,I.O., Xu,J., Liu,J. and Cameron,K.
    Synthesis and antiproliferative activity of sulfonamide-based peptidomimetic calpain inhibitors
    Bioorg Med Chem115433-115433. PubMed  Europe PubMed DOI  I
  21. Edwards,J.J., Brandimarto,J., Hu,D.Q., Jeong,S., Yucel,N., Li,L., Bedi,K.C., Jr., Wada,S., Murashige,D., Hwang,H.T.V., Zhao,M., Margulies,K.B., Bernstein,D., Reddy,S. and Arany,Z.
    Noncanonical WNT Activation in Human Right Ventricular Heart Failure
    Front Cardiovasc Med7, 582407-582407. PubMed  Europe PubMed DOI
  22. Goto,S., Ozaki,Y., Ozawa,F., Mizutani,E., Kitaori,T., Suzumori,N., Blomgren,K., Furuno,T. and Sugiura-Ogasawara,M.
    The investigation of calpain in human placenta with fetal growth restriction
    Am J Reprod Immunole13325-e13325. PubMed  Europe PubMed DOI
  23. Gritsyna,Y.V., Ulanova,A.D., Popova,S.S., Bobylev,A.G., Zhalimov,V.K., Nemirovskaya,T.L., Shenkman,B.S. and Vikhlyantsev,I.M.
    Inhibition of Histone Deacetylases 4 and 5 Reduces Titin Proteolysis and Prevents Reduction of TTN Gene Expression in Atrophied Rat Soleus Muscle after Seven-Day Hindlimb Unloading
    Dokl Biochem Biophys495, 338-341. PubMed  Europe PubMed DOI
  24. Hatta,D., Shirotani,K., Hori,Y., Kurotaki,N. and Iwata,N.
    Activity-dependent cleavage of dyskinesia-related proline-rich transmembrane protein 2 (PRRT2) by calpain in mouse primary cortical neurons
    FASEB J34, 180-191. PubMed  Europe PubMed DOI
  25. Jastaniah,A., Gaisina,I.N., Knopp,R.C. and Thatcher,G.R.J.
    Synthesis of alpha-Ketoamide-Based Stereoselective Calpain-1 Inhibitors as Neuroprotective Agents
    ChemMedChem PubMed  Europe PubMed DOI  I
  26. Ko,Y.U., Song,H.Y., Kim,W.K., Yune,T.Y., Yun,N. and Oh,Y.J.
    Calpain-mediated cleavage of Fbxw7 during excitotoxicity
    Neurosci Lett736, 135265-135265. PubMed  Europe PubMed DOI  I
  27. Lakshmanan,A., Jin,Z., Nety,S.P., Sawyer,D.P., Lee-Gosselin,A., Malounda,D., Swift,M.B., Maresca,D. and Shapiro,M.G.
    Acoustic biosensors for ultrasound imaging of enzyme activity
    Nat Chem Biol PubMed  Europe PubMed DOI
  28. Lopatniuk,P., Puchalska,Z., Mital,A., Mikosik,A., Frackowiak,J., Hellmann,A., Daca,A., Bryl,E., Fulop,T. and Witkowski,J.M.
    Excessive amount and activity of mu-calpain affects apoptotic machinery in chronic B-cell leukemia cells and influences the course of the disease
    Acta Biochim Pol67, 247-257. PubMed  Europe PubMed DOI
  29. Panico,P., Hiriart,M., Ostrosky-Wegman,P. and Salazar,A.M.
    TUG is a calpain-10 substrate involved in the translocation of GLUT4 in adipocytes
    J Mol Endocrinol65, 45-57. PubMed  Europe PubMed DOI
  30. Wang,Y., Liu,Y., Bi,X. and Baudry,M.
    Calpain-1 and Calpain-2 in the Brain: New Evidence for a Critical Role of Calpain-2 in Neuronal Death
    Cells9, PubMed  Europe PubMed DOI
  31. Weber,J.J., Haas,E., Maringer,Y., Hauser,S., Casadei,N.L.P., Chishti,A.H., Riess,O. and Hubener-Schmid,J.
    Calpain-1 ablation partially rescues disease-associated hallmarks in models of Machado-Joseph disease
    Hum Mol Genet29, 892-906. PubMed  Europe PubMed DOI  K
  32. Yi,C., Wu,W., Zheng,D., Peng,G., Huang,H., Shen,Z. and Teng,X.
    Targeted inhibition of endothelial calpain delays wound healing by reducing inflammation and angiogenesis
    Cell Death Dis11, 533-533. PubMed  Europe PubMed DOI
    33. 2019
  33. Antoniades,I., Charalambous,A., Christodoulou,N., Zanardelli,S. and Skourides,P.A.
    Methods of calpain inhibition to determine the role of calpains in embryo development in amphibians
    Methods Mol Biol1915, 249-259. PubMed  Europe PubMed DOI
  34. Baudry,M.
    Calpain-1 and calpain-2 in the brain: Dr. Jekill and Mr Hyde?
    Curr Neuropharmacol17, 823-829. PubMed  Europe PubMed DOI
  35. Biswas,A.K. and Tandon,S.
    Casein zymography for analysis of calpain-1 and calpain-2 activity
    Methods Mol Biol1915, 31-38. PubMed  Europe PubMed DOI
  36. Biswas,A.K. and Tandon,S.
    Single-step purification of calpain-1, calpain-2, and calpastatin using anion-exchange chromatography
    Methods Mol Biol1915, 3-11. PubMed  Europe PubMed DOI
  37. Chaimon,S., Limpanont,Y., Reamtong,O., Ampawong,S., Phuphisut,O., Chusongsang,P., Ruangsittichai,J., Boonyuen,U., Watthanakulpanich,D., O'Donoghue,A.J., Caffrey,C.R. and Adisakwattana,P.
    Molecular characterization and functional analysis of the Schistosoma mekongi Ca(2+)-dependent cysteine protease (calpain)
    Parasit Vectors12, 383-383. PubMed  Europe PubMed DOI
  38. Cotti Piccinelli,S., Bassi,M.T., Citterio,A., Manganelli,F., Tozza,S., Santorelli,F.M., Gallo Cassarino,S., Caria,F., Baldelli,E., Galvagni,A., Santoro,L., Padovani,A. and Filosto,M.
    A Novel CAPN1 Mutation Causes a Pure Hereditary Spastic Paraplegia in an Italian Family
    Front Neurol10, 580-580. PubMed  Europe PubMed DOI  M
  39. Davis,M.A., Fairgrieve,M.R., Den Hartigh,A., Yakovenko,O., Duvvuri,B., Lood,C., Thomas,W.E., Fink,S.L. and Gale M Jr
    Calpain drives pyroptotic vimentin cleavage, intermediate filament loss, and cell rupture that mediates immunostimulation
    Proc Natl Acad Sci U S A116, 5061-5070. PubMed  Europe PubMed DOI
  40. Del Carmen Lafita-Navarro,M. and Conacci-Sorrell,M.
    Identification of calpain-activated protein functions
    Methods Mol Biol1915, 149-160. PubMed  Europe PubMed DOI
  41. Du,M., Li,X., Li,Z., Shen,Q., Ren,C. and Zhang,D.
    Calpastatin inhibits the activity of phosphorylated mu-calpain in vitro
    Food Chem274, 743-749. PubMed  Europe PubMed DOI
  42. Duverle,D.A. and Mamitsuka,H.
    CalCleaveMKL: a tool for calpain cleavage prediction
    Methods Mol Biol1915, 121-147. PubMed  Europe PubMed DOI
  43. Gao,Y., Hall,C., MacLeod,J. and Greer,P.A.
    Genetic models of calpain deficiency and ectopic expression
    Methods Mol Biol1915, 261-274. PubMed  Europe PubMed DOI  K
  44. Jantos,K., Kling,A., Mack,H., Hornberger,W., Moeller,A., Nimmrich,V., Lao,Y. and Nijsen,M.
    Discovery of ABT-957: 1-benzyl-5-oxopyrrolidine-2-carboxamides as selective calpain inhibitors with enhanced metabolic stability
    Bioorg Med Chem Lett29, 1968-1973. PubMed  Europe PubMed DOI  I
  45. Jennings,S. and Hallett,M.B.
    Single cell measurement of calpain activity in neutrophils reveals link to cytosolic Ca(2+) elevation and individual phagocytotic events
    Biochem Biophys Res Commun515, 163-168. PubMed  Europe PubMed DOI  L
  46. Jiang,S., Shao,C., Tang,F., Wang,W. and Zhu,X.
    Dynamin-like protein 1 cleavage by calpain in Alzheimer's disease
    Aging Celle12912-e12912. PubMed  Europe PubMed DOI  I
  47. Jin,S.W., Lee,G.H., Pham,H.T., Choi,J.H. and Jeong,H.G.
    Polyhexamethylene guanidine phosphate damages tight junctions and the F-actin architecture by activating calpain-1 via the P2RX7/Ca(2+) signaling pathway
    Cells9, PubMed  Europe PubMed DOI
  48. Kitagawa,S.
    Experimental manipulation of calpain activity in vitro
    Methods Mol Biol1915, 209-218. PubMed  Europe PubMed DOI  I
  49. Liu,X. and Hu,G.
    In vivo calpain knockdown using delivery of siRNA
    Methods Mol Biol1915, 219-232. PubMed  Europe PubMed DOI  K
  50. Liu,Z.X., Yu,K., Dong,J., Zhao,L., Liu,Z., Zhang,Q., Li,S., Du,Y. and Cheng,H.
    Precise prediction of calpain cleavage sites and their aberrance caused by mutations in cancer
    Front Genet10, 715-715. PubMed  Europe PubMed DOI  P
  51. Lostal,W., Stockholm,D. and Richard,I.
    In vivo monitoring of calpain activity by Forster resonance energy transfer
    Methods Mol Biol1915, 57-66. PubMed  Europe PubMed DOI  L
  52. Matos,A.M., Pinto,F.R., Barros,P., Amaral,M.D., Pepperkok,R. and Matos,P.
    Inhibition of calpain 1 restores plasma membrane stability to pharmacologically rescued Phe508del-CFTR variant
    J Biol Chem294, 13396-13410. PubMed  Europe PubMed DOI
  53. Ong,S.B., Lee,W.H., Shao,N.Y., Ismail,N.I., Katwadi,K., Lim,M.M., Kwek,X.Y., Michel,N.A., Li,J., Newson,J., Tahmasebi,S., Rehman,J., Kodo,K., Jang,H.R. and Ong,S.G.
    Calpain inhibition restores autophagy and prevents mitochondrial fragmentation in a human iPSC model of diabetic endotheliopathy
    Stem Cell Reports12, 597-610. PubMed  Europe PubMed DOI  I
  54. Shams,R., Banik,N.L. and Haque,A.
    Calpain in the cleavage of alpha-synuclein and the pathogenesis of Parkinson's disease
    Prog Mol Biol Transl Sci167, 107-124. PubMed  Europe PubMed DOI
  55. Wang,L., Zhang,C., Sun,S., Chen,Y., Hu,Y., Wang,H., Liu,M., Dong,N. and Wu,Q.
    Autoactivation and calpain-1-mediated shedding of hepsin in human hepatoma cells
    Biochem J476, 2355-2369. PubMed  Europe PubMed DOI
    56. 2018
  56. Andersen,P.V., Wold,J.P. and Veiseth-Kent,E.
    Analyzing mu-Calpain induced proteolysis in a myofibril model system with vibrational and fluorescence spectroscopy
    Meat Sci139, 239-246. PubMed  Europe PubMed DOI
  57. Aweida,D., Rudesky,I., Volodin,A., Shimko,E. and Cohen,S.
    GSK3-beta promotes calpain-1-mediated desmin filament depolymerization and myofibril loss in atrophy
    J Cell Biol217, 3698-3714. PubMed  Europe PubMed DOI
  58. Becker,B., Nazir,F.H., Brinkmalm,G., Camporesi,E., Kvartsberg,H., Portelius,E., Bostrom,M., Kalm,M., Hoglund,K., Olsson,M., Zetterberg,H. and Blennow,K.
    Alzheimer-associated cerebrospinal fluid fragments of neurogranin are generated by calpain-1 and prolyl endopeptidase
    Mol Neurodegener13, 47-47. PubMed  Europe PubMed DOI
  59. Chen,H.H., Liu,P., Auger,P., Lee,S.H., Adolfsson,O., Rey-Bellet,L., Lafrance-Vanasse,J., Friedman,B.A., Pihlgren,M., Muhs,A., Pfeifer,A., Ernst,J., Ayalon,G., Wildsmith,K.R., Beach,T.G. and van der Brug,M.P.
    Calpain-mediated tau fragmentation is altered in Alzheimer's disease progression
    Sci Rep8, 16725-16725. PubMed  Europe PubMed DOI  P
  60. De Tullio,R., Franchi,A., Martines,A., Averna,M., Pedrazzi,M., Melloni,E. and Sparatore,B.
    Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain
    Biosci Rep38, BSR20180147-BSR20180147. PubMed  Europe PubMed DOI
  61. Du,M., Li,X., Li,Z., Shen,Q., Wang,Y., Li,G. and Zhang,D.
    Phosphorylation regulated by protein kinase A and alkaline phosphatase play positive roles in mu-calpain activity
    Food Chem252, 33-39. PubMed  Europe PubMed DOI
  62. Etwebi,Z., Landesberg,G., Preston,K., Eguchi,S. and Scalia,R.
    Mechanistic role of the calcium-dependent protease calpain in the endothelial dysfunction induced by MPO (myeloperoxidase)
    Hypertension71, 761-770. PubMed  Europe PubMed DOI  K
  63. Gutierrez,S., Moron,M., Griera,M., Sucunza,D., Calleros,L., Garcia-Jerez,A., Coderch,C., Hermoso,F.J., Burgos,C., Rodriguez-Puyol,M., de Pascual-Teresa,B., Diez-Marques,M.L., Jimenez,A., Toro-Londono,M., Rodriguez-Puyol,D. and Vaquero,J.J.
    Discovery of potent calpain inhibitors based on the azolo-imidazolidenone scaffold
    Eur J Med Chem157, 946-959. PubMed  Europe PubMed DOI  I
  64. Ishak,R. and Hallett,M.B.
    Defective rapid cell shape and transendothelial migration by calpain-1 null neutrophils
    Biochem Biophys Res Commun506, 1065-1070. PubMed  Europe PubMed DOI  K
  65. Kalash,L., Cresser-Brown,J., Habchi,J., Morgan,C., Miller,D.J., Glen,R.C., Allemann,R.K. and Bender,A.
    Structure-based design of allosteric calpain-1 inhibitors populating a novel bioactivity space
    Eur J Med Chem157, 1264-1275. PubMed  Europe PubMed DOI  I
  66. Kling,A., Jantos,K., Mack,H., Hornberger,W., Backfisch,G., Lao,Y., Nijsen,M., Rendenbach-Mueller,B. and Moeller,A.
    Mitigating the metabolic liability of carbonyl reduction: novel calpain inhibitors with P1' extension
    ACS Med Chem Lett9, 221-226. PubMed  Europe PubMed DOI  I
  67. Leal-Gutierrez,J.D., Elzo,M.A., Johnson,D.D., Scheffler,T.L., Scheffler,J.M. and Mateescu,R.G.
    Association of mu-calpain and calpastatin polymorphisms with meat tenderness in a Brahman-Angus population
    Front Genet9, 56-56. PubMed  Europe PubMed DOI  M
  68. MacLeod,J.A., Gao,Y., Hall,C., Muller,W.J., Gujral,T.S. and Greer,P.A.
    Genetic disruption of calpain-1 and calpain-2 attenuates tumorigenesis in mouse models of HER2+ breast cancer and sensitizes cancer cells to doxorubicin and lapatinib
    Oncotarget9, 33382-33395. PubMed  Europe PubMed DOI  K  I
  69. Nowak,K., Taubert,R.M., Haberecht,S., Venz,S. and Kruger,E.
    Inhibition of calpain-1 stabilizes TCF11/Nrf1 but does not affect its activation in response to proteasomal inhibition
    Biosci Rep38, BSR20180393-BSR20180393. PubMed  Europe PubMed DOI
  70. Pahima,H., Reina,S., Tadmor,N., Dadon-Klein,D., Shteinfer-Kuzmine,A., Mazure,N.M., Pinto,V. and Shoshan-Barmatz,V.
    Hypoxic-induced truncation of voltage-dependent anion channel 1 is mediated by both asparagine endopeptidase and calpain 1 activities
    Oncotarget9, 12825-12841. PubMed  Europe PubMed DOI  I
  71. Salimi,R., Bandaru,S., Devarakonda,S., Gokalp,S., Ala,C., Alvandian,A., Yener,N. and Akyurek,L.M.
    Blocking the cleavage of filamin A by calpain inhibitor decreases tumor cell growth
    Anticancer Res38, 2079-2085. PubMed  Europe PubMed DOI  I
  72. Verheijden,K.A.T., Sonneveld,R., Bakker-van Bebber,M., Wetzels,J.F.M., van der Vlag,J. and Nijenhuis,T.
    The calcium-dependent protease calpain-1 links TRPC6 activity to podocyte injury
    J Am Soc Nephrol29, 2099-2109. PubMed  Europe PubMed DOI
  73. Wang,Y., Chen,B., Huang,C.K., Guo,A., Wu,J., Zhang,X., Chen,R., Chen,C., Kutschke,W., Weiss,R.M., Boudreau,R.L., Margulies,K.B., Hong,J. and Song,L.S.
    Targeting calpain for heart failure therapy: implications from multiple murine models
    JACC Basic Transl Sci3, 503-517. PubMed  Europe PubMed DOI  I
  74. Wang,Y., Liu,Y., Lopez,D., Lee,M., Dayal,S., Hurtado,A., Bi,X. and Baudry,M.
    Protection against TBI-induced neuronal death with post-treatment with a selective calpain-2 inhibitor in mice
    J Neurotrauma35, 105-117. PubMed  Europe PubMed DOI  I
    75. 2017
  75. Du,M., Li,X., Li,Z., Li,M., Gao,L. and Zhang,D.
    Phosphorylation inhibits the activity of mu-calpain at different incubation temperatures and Ca2+ concentrations in vitro
    Food Chem228, 649-655. PubMed  Europe PubMed DOI
  76. Du,M., Li,X., Li,Z., Shen,Q., Wang,Y., Li,G. and Zhang,D.
    Effects of phosphorylation on mu-calpain activity at different incubation temperature
    Food Res Int100, 318-324. PubMed  Europe PubMed DOI
  77. Ferreras,S., Fernandez,G., Danelon,V., Pisano,M.V., Masseroni,L., Chapleau,C.A., Krapacher,F.A., Mlewski,E.C., Masco,D.H., Arias,C., Pozzo-Miller,L. and Paglini,M.G.
    Cdk5 is essential for amphetamine to increase dendritic spine density in hippocampal pyramidal neurons
    Front Cell Neurosci11, 372-372. PubMed  Europe PubMed DOI  I
  78. Hsu,C.Y., Gasc,G., Raymond,A.A., Burlet-Schiltz,O., Takahara,H., Serre,G., Mechin,M.C. and Simon,M.
    Deimination of human hornerin enhances its processing by calpain-1 and its cross-linking by transglutaminases
    J Invest Dermatol137, 422-429. PubMed  Europe PubMed DOI
  79. Kerstein,P.C., Patel,K.M. and Gomez,T.M.
    Calpain-mediated proteolysis of talin and FAK regulates adhesion dynamics necessary for axon guidance
    J Neurosci37, 1568-1580. PubMed  Europe PubMed DOI
  80. Kling,A., Jantos,K., Mack,H., Hornberger,W., Drescher,K., Nimmrich,V., Relo,A., Wicke,K., Hutchins,C.W., Lao,Y., Marsh,K. and Moeller,A.
    Discovery of novel and highly selective inhibitors of calpain for the treatment of Alzheimer's disease: 2-(3-phenyl-1H-pyrazol-1-yl)-nicotinamides
    J Med Chem60, 7123-7138. PubMed  Europe PubMed DOI  I
  81. Li,J., Yang,S. and Zhu,G.
    Postnatal calpain inhibition elicits cerebellar cell death and motor dysfunction
    Oncotarget8, 87997-88007. PubMed  Europe PubMed DOI  I
  82. Li,Z., Li,X., Gao,X., Du,M. and Zhang,D.
    Effect of inhibition of mu-calpain on the myofibril structure and myofibrillar protein degradation in postmortem ovine muscle
    J Sci Food Agric97, 2122-2131. PubMed  Europe PubMed DOI  I
  83. Li,Z., Li,X., Gao,X., Shen,Q.W., Du,M. and Zhang,D.
    Phosphorylation prevents in vitro myofibrillar proteins degradation by mu-calpain
    Food Chem218, 455-462. PubMed  Europe PubMed DOI
  84. Lin,X.Y. and Chen,S.Z.
    Calpain inhibitors ameliorate muscle wasting in a cachectic mouse model bearing CT26 colorectal adenocarcinoma
    Oncol Rep37, 1601-1610. PubMed  Europe PubMed DOI  I
  85. Liu,W., Ma,K., Kwon,S.H., Garg,R., Patta,Y.R., Fujiwara,T. and Gurtner,G.C.
    The abnormal architecture of healed diabetic ulcers is the result of FAK degradation by calpain 1
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  265. Davis,T.L., Walker,J.R., Finerty,P.J., Jr., Mackenzie,F., Newman,E.M. and Dhe-Paganon,S.
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  266. Dufty,B.M., Warner,L.R., Hou,S.T., Jiang,S.X., Gomez-Isla,T., Leenhouts,K.M., Oxford,J.T., Feany,M.B., Masliah,E. and Rohn,T.T.
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  267. Goni-Oliver,P., Lucas,J.J., Avila,J. and Hernandez,F.
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  268. Haacke,A., Hartl,F.U. and Breuer,P.
    Calpain inhibition is sufficient to suppress aggregation of polyglutamine-expanded ataxin-3
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  269. Harper,A.G. and Sage,S.O.
    A role for the intracellular protease calpain in the activation of store-operated calcium entry in human platelets
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  270. Kuchay,S.M., Kim,N., Grunz,E.A., Fay,W.P. and Chishti,A.H.
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  271. Mellgren,R.L., Zhang,W., Miyake,K. and McNeil,P.L.
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  272. Saito,M., Li,H., Thompson,V.F., Kunisaki,N. and Goll,D.E.
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  276. Yaroslavskiy,B.B., Sharrow,A.C., Wells,A., Robinson,L.J. and Blair,H.C.
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    278. 2006
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  281. Geesink,G.H., Kuchay,S., Chishti,A.H. and Koohmaraie,M.
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  282. Guan,N., Korukonda,R., Hurh,E., Schmittgen,T.D., Donkor,I.O. and Dalton,J.T.
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  285. Lebart,M.C. and Benyamin,Y.
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  288. [YEAR:27-10-2006]Raynaud,F., Fabrice,R., Jond-Necand,C., Carole,J.N., Marcilhac,A., Anne,M., Furst,D., Dieter,F., Benyamin,Y. and Yves,B.
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  291. Shirasaki,Y., Yamaguchi,M. and Miyashita,H.
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  293. Weyermann,P., Herzner,H., Lescop,C., Siendt,H., Bolliger,R., Hennebohle,M., Rummey,C. and Meier,T.
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  295. [YEAR:26-9-2006]Zhang,Z., Biesiadecki,B.J. and Jin,J.P.
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  296. Arataki,S., Tomizawa,K., Moriwaki,A., Nishida,K., Matsushita,M., Ozaki,T., Kunisada,T., Yoshida,A., Inoue,H. and Matsui,H.
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  297. [YEAR:13-5-2005]Chen,M. and Fernandez,H.L.
    mu-Calpain is functionally required for alpha-processing of Alzheimer's beta-amyloid precursor protein
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  299. [YEAR:20-6-2005]Das,A., Sribnick,E.A., Wingrave,J.M., Del Re,A.M., Woodward,J.J., Appel,S.H., Banik,N.L. and Ray,S.K.
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  300. [YEAR:24-10-2005]Garcia,M., Bondada,V. and Geddes,J.W.
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  302. Hayashi,M., Koshihara,Y., Ishibashi,H., Yamamoto,S., Tsubuki,S., Saido,T.C., Kawashima,S. and Inomata,M.
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  303. Higuchi,M., Tomioka,M., Takano,J., Shirotani,K., Iwata,N., Masumoto,H., Maki,M., Itohara,S. and Saido,T.C.
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  305. Liu,F., Grundke-Iqbal,I., Iqbal,K., Oda,Y., Tomizawa,K. and Gong,C.X.
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  306. [YEAR:31-5-2005]Mishizen-Eberz,A.J., Norris,E.H., Giasson,B.I., Hodara,R., Ischiropoulos,H., Lee,V.M., Trojanowski,J.Q. and Lynch,D.R.
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  308. [YEAR:7-12-2005]Polster,B.M., Basanez,G., Etxebarria,A., Hardwick,J.M. and Nicholls,D.G.
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  309. Raynaud,F., Fernandez,E., Coulis,G., Aubry,L., Vignon,X., Bleimling,N., Gautel,M., Benyamin,Y. and Ouali,A.
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  310. Salem,M., Nath,J., Rexroad,C.E., Killefer,J. and Yao,J.
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  312. Takano,J., Tomioka,M., Tsubuki,S., Higuchi,M., Iwata,N., Itohara,S., Maki,M. and Saido,T.C.
    Calpain mediates excitotoxic DNA fragmentation via mitochondrial pathways in adult brains: evidence from calpastatin mutant mice
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    Calpain-1 regulates Bax and subsequent Smac-dependent caspase-3 activation in neutrophil apoptosis
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  316. [YEAR:22-10-2004]Farkas,B., Tantos,A., Schlett,K., Vilagi,I. and Friedrich,P.
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  317. [YEAR:4-6-2004]Fernandez-Montalvan,A., Assfalg-Machleidt,I., Pfeiler,D., Fritz,H., Jochum,M. and Machleidt,W.
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  318. Franco,S.J., Rodgers,M.A., Perrin,B.J., Han,J.W., Bennin,D.A., Critchley,D.R. and Huttenlocher,A.
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  326. Montero,A., Mann,E., Chana,A. and Herradon,B.
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  327. Moyen,C., Goudenege,S., Poussard,S., Sassi,A.H., Brustis,J.J. and Cottin,P.
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  328. Page,B.T., Casas,E., Quaas,R.L., Thallman,R.M., Wheeler,T.L., Shackelford,S.D., Koohmaraie,M., White,S.N., Bennett,G.L., Keele,J.W., Dikeman,M.E. and Smith,T.P.
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  343. Pal,G.P., De Veyra,T., Elce,J.S. and Jia,Z.
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