Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q9NTZ6

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
384	cathepsin L	381-392	N		MS	Biniossek et al., 2011
384	cathepsin S	381-392	N		MS	Biniossek et al., 2011
399	matrix metallopeptidase-2	392-410	N		MS	Schilling & Overall, 2008
410	trypsin 1	1-932	N		MS	Schilling & Overall, 2008
529	trypsin 1	1-932	N		MS	Schilling & Overall, 2008
543	trypsin 1	1-932	N		MS	Schilling & Overall, 2008
554	matrix metallopeptidase-2	538-565	N		MS	Schilling & Overall, 2008
565	glutamyl endopeptidase I	1-932	N		MS	Schilling & Overall, 2008
841	cathepsin L	752-859	N		MS	Biniossek et al., 2011
845	cathepsin B	752-859	N		MS	Biniossek et al., 2011
845	matrix metallopeptidase-2	751-859	N		MS	Schilling & Overall, 2008
847	cathepsin L	752-859	N		MS	Biniossek et al., 2011
847	cathepsin S	752-859	N		MS	Biniossek et al., 2011
848	cathepsin S	752-859	N		MS	Biniossek et al., 2011
848	cathepsin B	752-859	N		MS	Biniossek et al., 2011
859	trypsin 1	1-932	N		MS	Schilling & Overall, 2008