Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence Q9H583

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-2144	P	release of an initiating methionine	MS	Van Damme P et al., 2005
68	matrix metallopeptidase-2	66-78	N		MS	Schilling & Overall, 2008
78	glutamyl endopeptidase I	1-2144	N		MS	Schilling & Overall, 2008
1015	peptidyl-Lys metallopeptidase	1-2144	N		MS
1043	peptidyl-Lys metallopeptidase	1-2144	N		MS
1361	granzyme B (Homo sapiens-type)	1-2144	N		MS	Van Damme et al., 2010
1680	cathepsin L	1680-1690	N		MS	Biniossek et al., 2011