Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q9GZV9

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
24	unknown peptidase	1-251	P	release of a signal peptide	NT	Zhang & Henzel, 2004
179	furin	174-183	N		CS	Remacle et al., 2008
179	PCSK2 peptidase	174-183	N		CS	Remacle et al., 2008
179	PCSK4 peptidase	174-183	N		CS	Remacle et al., 2008
179	PCSK6 peptidase	174-183	N		CS	Remacle et al., 2008
179	PCSK5 peptidase	174-183	N		CS	Remacle et al., 2008
179	PCSK7 peptidase	174-183	N		CS	Remacle et al., 2008