Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q96G03

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-612	P		NT	<%Agarwal et al., 2012[]%>
22	matrix metallopeptidase-2	18-33	N		MS	Schilling & Overall, 2008
33	glutamyl endopeptidase I	2-612	N		MS	Schilling & Overall, 2008
178	cathepsin L	176-190	N		MS	Biniossek et al., 2011
390	trypsin 1	2-612	N		MS	Schilling & Overall, 2008
403	trypsin 1	2-612	N		MS	Schilling & Overall, 2008
522	cathepsin L	520-533	N		MS	Biniossek et al., 2011
522	cathepsin S	520-533	N		MS	Biniossek et al., 2011
586	trypsin 1	2-612	N		MS	Schilling & Overall, 2008
590	matrix metallopeptidase-2	586-604	N		MS	Schilling & Overall, 2008
604	trypsin 1	2-612	N		MS	Schilling & Overall, 2008