Searches of the MEROPS database

Display Known Cleavages for a Protein

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Sequence Q86V81

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Evidence	Reference
1	unknown peptidase	1-257	P	NT	<%Agarwal et al., 2012[]%>
3	granzyme B (Homo sapiens-type)	2-257	N	MS	Van Damme et al., 2010
4	trypsin 1	2-257	N	MS	Schilling & Overall, 2008
10	granzyme B (Homo sapiens-type)	2-257	N	MS	Van Damme et al., 2010
14	trypsin 1	2-257	N	MS	Schilling & Overall, 2008
90	caspase-1	2-257	N	MS	Agard et al., 2010
92	meprin alpha subunit	89-107	N	MS	Becker-Pauly et al., 2011
93	cathepsin S	87-107	N	MS	Biniossek et al., 2011
93	astacin	90-107	N	MS	Becker-Pauly et al., 2011
95	cathepsin B	87-107	N	MS	Biniossek et al., 2011
97	cathepsin S	87-107	N	MS	Biniossek et al., 2011
147	cathepsin L	145-155	N	MS	Biniossek et al., 2011
147	cathepsin S	145-155	N	MS	Biniossek et al., 2011
147	cathepsin K	144-155	N	MS	Schilling & Overall, 2008
155	trypsin 1	2-257	N	MS	Schilling & Overall, 2008
177	matrix metallopeptidase-2	164-189	N	MS	Schilling & Overall, 2008
189	trypsin 1	2-257	N	MS	Schilling & Overall, 2008
207	cathepsin B	205-216	N	MS	Biniossek et al., 2011
235	trypsin 1	2-257	N	MS	Schilling & Overall, 2008
241	granzyme B (Homo sapiens-type)	2-257	N	MS	Van Damme et al., 2010
248	granzyme B (Homo sapiens-type)	2-257	N	MS	Van Damme et al., 2010
253	trypsin 1	2-257	N	MS	Schilling & Overall, 2008