Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q7L2H7

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-374	P		NT	<%Agarwal et al., 2012[]%>
23	lysyl endopeptidase (bacteria)	1-374	N		MS
149	trypsin 1	2-374	N		MS	Schilling & Overall, 2008
160	trypsin 1	2-374	N		MS	Schilling & Overall, 2008
187	cathepsin B	184-199	N		MS	Biniossek et al., 2011
189	cathepsin S	184-201	N		MS	Biniossek et al., 2011
190	cathepsin L	184-201	N		MS	Biniossek et al., 2011
306	granzyme B (Homo sapiens-type)	2-374	N		MS	Van Damme et al., 2010