Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q76LX8

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
29	unknown peptidase	1-1427	P		NT	<%Agarwal et al., 2012[]%>
74	furin	69-78	N		CS	Remacle et al., 2008
74	PCSK2 peptidase	69-78	N		CS	Remacle et al., 2008
74	PCSK4 peptidase	69-78	N		CS	Remacle et al., 2008
74	PCSK6 peptidase	69-78	N		CS	Remacle et al., 2008
74	PCSK5 peptidase	69-78	N		CS	Remacle et al., 2008
74	PCSK7 peptidase	69-78	N		CS	Remacle et al., 2008
257	thrombin	75-1427	P		NT	Lam et al., 2007
1176	thrombin	75-1427	P		NT	Lam et al., 2007