Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence Q15149

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-4684	P	release of an initiating methionine	MS
1175	lysyl endopeptidase (bacteria)	1-4684	N		MS
1201	meprin alpha subunit	1-4684	N		MS	Becker-Pauly et al., 2011
1210	lysyl endopeptidase (bacteria)	1-4684	N		MS
2395	caspase-8	1-4684	P			Stegh et al., 2000
2397	caspase-8	1-4684	P			Stegh et al., 2000
2957	meprin beta subunit	2954-2968	N		MS	Becker-Pauly et al., 2011
2960	trypsin 1	1-4684	N		MS	Schilling & Overall, 2008
2968	trypsin 1	1-4684	N		MS	Schilling & Overall, 2008
4421	meprin alpha subunit	1-4684	N		MS	Becker-Pauly et al., 2011
4421	meprin beta subunit	1-4684	N		MS	Becker-Pauly et al., 2011
4683	carboxypeptidase A4	1-4684	N		MS	Van Damme et al., 2010