Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence Q14C86

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-1478	P	release of an initiating methionine	MS	Bantscheff et al., 2007
61	cathepsin L	58-75	N		MS	Biniossek et al., 2011
465	LAST_MAM peptidase (Limulus-type)	462-475	N		MS	Becker-Pauly et al., 2011
616	cathepsin L	583-629	N		MS	Biniossek et al., 2011
832	cathepsin L	797-844	N		MS	Biniossek et al., 2011
901	granzyme A	1-1478	N			Van Damme et al., 2010
1009	granzyme B (Homo sapiens-type)	1-1478	N		MS	Van Damme et al., 2010
1098	granzyme B (Homo sapiens-type)	1-1478	N		MS	Van Damme et al., 2010
1102	unknown peptidase		P		MS	Mahrus et al., 2008
1327	trypsin 1	1-1478	N		MS	Schilling & Overall, 2008
1340	trypsin 1	1-1478	N		MS	Schilling & Overall, 2008