Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q14563

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
20	unknown peptidase	1-771	P		NT	<%Agarwal et al., 2012[]%>
555	furin	550-559	N		CS	Remacle et al., 2008
555	PCSK2 peptidase	550-559	N		CS	Remacle et al., 2008
555	PCSK4 peptidase	550-559	N		CS	Remacle et al., 2008
555	PCSK6 peptidase	550-559	N		CS	Remacle et al., 2008
555	PCSK5 peptidase	550-559	N		CS	Remacle et al., 2008
555	PCSK7 peptidase	550-559	N		CS	Remacle et al., 2008