Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence Q12904

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-312	P	release of an initiating methionine	MS	Van Damme P et al., 2005
142	cathepsin S	138-154	N		MS	Biniossek et al., 2011
146	unknown peptidase	1-312	P		NT	<%Agarwal et al., 2012[]%>
172	granzyme B (Homo sapiens-type)	1-312	N		MS	Van Damme et al., 2010
187	trypsin 1	1-312	N		MS	Schilling & Overall, 2008
192	matrix metallopeptidase-2	187-205	N		MS	Schilling & Overall, 2008
205	trypsin 1	1-312	N		MS	Schilling & Overall, 2008
254	cathepsin L	251-267	N		MS	Biniossek et al., 2011
254	cathepsin S	251-267	N		MS	Biniossek et al., 2011
254	astacin	251-267	N		MS	Becker-Pauly et al., 2011