Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q07954

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
19	unknown peptidase	1-4544	P		NT	<%Agarwal et al., 2012[]%>
1911	lysyl endopeptidase (bacteria)	1-4544	N		MS
1950	lysyl endopeptidase (bacteria)	1-4544	N		MS
3943	furin	20-4544	P			Willnow et al., 1996
3943	PCSK2 peptidase	3938-3947	N		CS	Remacle et al., 2008
3943	PCSK4 peptidase	3938-3947	N		CS	Remacle et al., 2008
3943	PCSK6 peptidase	3938-3947	N		CS	Remacle et al., 2008
3943	PCSK5 peptidase	3938-3947	N		CS	Remacle et al., 2008
3943	PCSK7 peptidase	3938-3947	N		CS	Remacle et al., 2008