Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q07325

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
22	unknown peptidase	1-125	P	release of a signal peptide	NT	Tensen et al., 1999
24	dipeptidyl-peptidase IV (eukaryote)	23-125	P			Lambeir et al., 2001
112	matrix metallopeptidase-9	23-125	P	normal turnover		Van den Steen et al., 2003
112	matrix metallopeptidase-7	23-125	P	normal turnover		Cox et al., 2008
112	matrix metallopeptidase-12	23-125	P	normal turnover		Cox et al., 2008
115	matrix metallopeptidase-9	23-125	P	normal turnover		Van den Steen et al., 2003
116	matrix metallopeptidase-9	23-125	P	normal turnover		Van den Steen et al., 2003