Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q05513

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
210	caspase-3	1-592	P	normal turnover		Smith et al., 2000
210	caspase-7	1-592	P			Smith et al., 2000
210	caspase-6	1-592	P			Smith et al., 2000
210	caspase-8	1-592	P			Smith et al., 2000
230	caspase-7	1-592	P			Smith et al., 2000
239	caspase-3	1-592	P	normal turnover		Smith et al., 2000