Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q05397

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-1052	P		NT	<%Agarwal et al., 2012[]%>
704	caspase-6	2-1052	P			Gervais et al., 1998
704	granzyme B (Homo sapiens-type)	2-1052	P			Gervais et al., 1998
772	caspase-3	2-1052	P			Gervais et al., 1998
772	caspase-7	2-1052	P			Wen et al., 1997
772	caspase-6	2-1052	P			Gervais et al., 1998
1032	trypsin 1	2-1052	N		MS	Schilling & Overall, 2008
1042	trypsin 1	2-1052	N		MS	Schilling & Overall, 2008