Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence Q05320

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
32	unknown peptidase	1-676	P		NT	<%Agarwal et al., 2012[]%>
501	furin	495-504	P			Basak et al., 2001
501	PCSK2 peptidase	496-505	N		CS	Remacle et al., 2008
501	PCSK4 peptidase	496-505	N		CS	Remacle et al., 2008
501	PCSK6 peptidase	496-505	N		CS	Remacle et al., 2008
501	PCSK5 peptidase	496-505	N		CS	Remacle et al., 2008
501	PCSK7 peptidase	496-505	N		CS	Remacle et al., 2008
637	unknown peptidase	1-676	P		NT	<%Agarwal et al., 2012[]%>