Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P82979

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-210	P		NT	<%Agarwal et al., 2012[]%>
64	glutamyl endopeptidase I	37-80	N		MS	Schilling & Overall, 2008
80	trypsin 1	2-210	N		MS	Schilling & Overall, 2008
109	trypsin 1	2-210	N		MS	Schilling & Overall, 2008
119	trypsin 1	2-210	N		MS	Schilling & Overall, 2008
136	matrix metallopeptidase-2	117-152	N		MS	Schilling & Overall, 2008
138	astacin	135-149	N		MS	Becker-Pauly et al., 2011
138	meprin alpha subunit	2-210	N		MS	Becker-Pauly et al., 2011
139	meprin beta subunit	136-151	N		MS	Becker-Pauly et al., 2011
152	glutamyl endopeptidase I	2-210	N		MS	Schilling & Overall, 2008
185	cathepsin L	181-200	N		MS	Biniossek et al., 2011
185	cathepsin S	181-199	N		MS	Biniossek et al., 2011
186	cathepsin B	181-200	N		MS	Biniossek et al., 2011