Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P78536

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
17	unknown peptidase	1-824	P	release of a signal peptide	MS	Flikka et al., 2006
214	PCSK2 peptidase	209-218	N		CS	Remacle et al., 2008
214	PCSK4 peptidase	209-218	N		CS	Remacle et al., 2008
214	PCSK6 peptidase	209-218	N		CS	Remacle et al., 2008
214	PCSK5 peptidase	209-218	N		CS	Remacle et al., 2008
214	PCSK7 peptidase	209-218	N		CS	Remacle et al., 2008