Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P68082

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-154	P		NT	<%Agarwal et al., 2012[]%>
4	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
7	pepsin A	2-154	N		MS	Zhang et al., 2008
7	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
7	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
8	pepsin A	2-154	N		MS	Zhang et al., 2008
9	pepsin A	2-154	N		MS	Zhang et al., 2008
9	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
10	pepsin A	2-154	N		MS	Zhang et al., 2008
10	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
11	pepsin A	2-154	N		MS	Zhang et al., 2008
11	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
12	pepsin A	2-154	N		MS	Zhang et al., 2008
12	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
14	pepsin A	2-154	N		MS	Zhang et al., 2008
14	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
15	pepsin A	2-154	N		MS	Zhang et al., 2008
16	pepsin A	2-154	N		MS	Zhang et al., 2008
17	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
18	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
19	pepsin A	2-154	N		MS	Zhang et al., 2008
19	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
20	pepsin A	2-154	N		MS	Zhang et al., 2008
20	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
21	pepsin A	2-154	N		MS	Zhang et al., 2008
21	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
21	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
28	pepsin A	2-154	N		MS	Zhang et al., 2008
29	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
30	pepsin A	2-154	N		MS	Zhang et al., 2008
30	cathepsin D	2-153	P	normal turnover	NT	Beck et al., 2001
30	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
31	pepsin A	2-154	N		MS	Zhang et al., 2008
31	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
32	pepsin A	2-154	N		MS	Zhang et al., 2008
32	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
32	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
32	trypsin 1	2-154	N			Fontana et al., 1997
33	pepsin A	2-154	N		MS	Zhang et al., 2008
33	cathepsin D	2-153	P	normal turnover	NT	Beck et al., 2001
33	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
33	thermolysin	2-154	N			Fontana et al., 1997
34	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
35	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
36	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
37	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
37	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
40	pepsin A	2-154	N		MS	Zhang et al., 2008
41	pepsin A	2-154	N		MS	Zhang et al., 2008
41	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
43	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
44	pepsin A	2-154	N		MS	Zhang et al., 2008
45	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
46	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
47	pepsin A	2-154	N		MS	Zhang et al., 2008
49	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
53	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
55	pepsin A	2-154	N		MS	Zhang et al., 2008
55	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
56	pepsin A	2-154	N		MS	Zhang et al., 2008
56	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
60	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
61	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
61	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
64	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
65	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
68	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
69	pepsin A	2-154	N		MS	Zhang et al., 2008
69	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
69	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
70	pepsin A	2-154	N		MS	Zhang et al., 2008
70	cathepsin D	2-153	P	normal turnover	NT	Beck et al., 2001
70	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
72	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
73	cathepsin D	2-153	P	normal turnover	NT	Beck et al., 2001
73	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
74	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
75	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
76	pepsin A	2-154	N		MS	Zhang et al., 2008
76	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
76	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
77	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
78	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
84	pepsin A	2-154	N		MS	Zhang et al., 2008
84	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
85	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
86	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
87	pepsin A	2-154	N		MS	Zhang et al., 2008
88	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
89	pepsin A	2-154	N		MS	Zhang et al., 2008
89	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
89	thermolysin	2-154	N			Fontana et al., 1997
90	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
90	chymotrypsin A (cattle-type)	2-154	N			Fontana et al., 1997
90	subtilisin Carlsberg	2-154	N			Fontana et al., 1997
92	subtilisin Carlsberg	2-154	N			Fontana et al., 1997
93	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
94	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
94	subtilisin Carlsberg	2-154	N			Fontana et al., 1997
97	trypsin 1	2-154	N			Fontana et al., 1997
103	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
103	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
104	pepsin A	2-154	N		MS	Zhang et al., 2008
105	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
106	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
106	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
107	pepsin A	2-154	N		MS	Zhang et al., 2008
107	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
107	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
109	pepsin A	2-154	N		MS	Zhang et al., 2008
109	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
110	pepsin A	2-154	N		MS	Zhang et al., 2008
110	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
111	pepsin A	2-154	N		MS	Zhang et al., 2008
113	pepsin A	2-154	N		MS	Zhang et al., 2008
114	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
114	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
116	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
116	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
117	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
119	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
120	pepsin A	2-154	N		MS	Zhang et al., 2008
120	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
122	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
124	pepsin A	2-154	N		MS	Zhang et al., 2008
126	pepsin A	2-154	N		MS	Zhang et al., 2008
129	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
132	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
133	pepsin A	2-154	N		MS	Zhang et al., 2008
133	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
134	pepsin A	2-154	N		MS	Zhang et al., 2008
134	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
134	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
135	pepsin A	2-154	N		MS	Zhang et al., 2008
135	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
136	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
137	pepsin A	2-154	N		MS	Zhang et al., 2008
137	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
137	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
138	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
141	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
142	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
144	pepsin A	2-154	N		MS	Zhang et al., 2008
145	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
145	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
146	pepsin A	2-154	N		MS	Zhang et al., 2008
146	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
146	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
147	pepsin A	2-154	N		MS	Zhang et al., 2008
149	rhizopuspepsin	2-154	N		MS	Zhang et al., 2008
150	aspergillopepsin I	2-154	N		MS	Zhang et al., 2008
152	pepsin A	2-154	N		MS	Zhang et al., 2008