Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P62854

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-115	P		NT	<%Agarwal et al., 2012[]%>
28	granzyme A	1-115	N			Van Damme et al., 2010
34	granzyme A	1-115	N			Van Damme et al., 2010
104	cathepsin L	101-115	N		MS	Biniossek et al., 2011
105	meprin alpha subunit	102-115	N		MS	Becker-Pauly et al., 2011
105	LAST peptidase (Limulus-type)	102-115	N		MS	Becker-Pauly et al., 2011
105	LAST_MAM peptidase (Limulus-type)	102-115	N		MS	Becker-Pauly et al., 2011
106	astacin	103-115	N		MS	Becker-Pauly et al., 2011