Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P62081

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
26	elastase-2	15-37	N		MS	Schilling & Overall, 2008
33	unknown peptidase	1-194	P			Van Damme et al., 2009
36	peptidyl-Lys metallopeptidase	1-194	N		MS
37	trypsin 1	1-194	N		MS	Schilling & Overall, 2008
41	trypsin 1	1-194	N			Van Damme et al., 2009
48	peptidyl-Lys metallopeptidase	1-194	N		MS
120	trypsin 1	1-194	N		MS	Schilling & Overall, 2008
131	meprin alpha subunit	1-194	N		MS	Becker-Pauly et al., 2011
131	meprin beta subunit	128-141	N		MS	Becker-Pauly et al., 2011
131	LAST_MAM peptidase (Limulus-type)	128-142	N		MS	Becker-Pauly et al., 2011
132	caspase-1	1-194	N		MS	Agard et al., 2010
142	trypsin 1	1-194	N		MS	Schilling & Overall, 2008