Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P61353

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-136	P		NT	<%Agarwal et al., 2012[]%>
38	LAST_MAM peptidase (Limulus-type)	35-51	N		MS	Becker-Pauly et al., 2011
73	trypsin 1	2-136	N		MS	Schilling & Overall, 2008
76	cathepsin S	74-84	N		MS	Biniossek et al., 2011
84	trypsin 1	2-136	N		MS	Schilling & Overall, 2008
93	trypsin 1	2-136	N		MS	Schilling & Overall, 2008
97	peptidyl-Lys metallopeptidase	1-136	N		MS
99	caspase-1	2-136	N		MS	Agard et al., 2010
106	peptidyl-Lys metallopeptidase	1-136	N		MS
114	peptidyl-Lys metallopeptidase	1-136	N		MS
122	peptidyl-Lys metallopeptidase	1-136	N		MS