Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P55210

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-303	P		NT	<%Agarwal et al., 2012[]%>
23	caspase-3	1-303	P	release of an activation peptide		Yang etal, 1998
23	caspase-7	1-303	P			Yang et al., 1999
36	calpain-1	24-198	P		MS	Gafni et al., 2009
45	calpain-1	24-198	P		MS	Gafni et al., 2009
47	calpain-1	24-198	P		MS	Gafni et al., 2009
198	caspase-6	1-303	P			Lippke et al., 1996
198	granzyme B (Homo sapiens-type)	1-303	P			Yang et al., 1999
206	caspase-6	1-303	P			Lippke et al., 1996