Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P52480

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-531	P		NT	<%Agarwal et al., 2012[]%>
12	matrix metallopeptidase-2	2-531	N		MS	auf dem Keller et al., 2010
17	matrix metallopeptidase-2	2-531	N		MS	Prudova et al., 2010
21	matrix metallopeptidase-2	2-531	N		MS	Prudova et al., 2010
33	cathepsin D	2-531	P		MS	Impens et al., 2010
33	cathepsin E	2-531	P		MS	Impens et al., 2010
59	cathepsin D	2-531	P		MS	Impens et al., 2010
59	cathepsin E	2-531	P		MS	Impens et al., 2010
60	cathepsin D	2-531	P		MS	Impens et al., 2010
60	cathepsin E	2-531	P		MS	Impens et al., 2010
61	cathepsin D	2-531	P		MS	Impens et al., 2010
63	cathepsin D	2-531	P		MS	Impens et al., 2010
63	cathepsin E	2-531	P		MS	Impens et al., 2010
64	cathepsin D	2-531	P		MS	Impens et al., 2010
64	cathepsin E	2-531	P		MS	Impens et al., 2010
98	cathepsin E	2-531	P		MS	Impens et al., 2010
109	cathepsin D	2-531	P		MS	Impens et al., 2010
109	cathepsin E	2-531	P		MS	Impens et al., 2010
109	matrix metallopeptidase-2	2-531	N		MS	Prudova et al., 2010
110	cathepsin E	2-531	P		MS	Impens et al., 2010
264	matrix metallopeptidase-2	2-531	N		MS	auf dem Keller et al., 2010
270	matrix metallopeptidase-2	2-531	N		MS	auf dem Keller et al., 2010
282	cathepsin E	2-531	P		MS	Impens et al., 2010
282	matrix metallopeptidase-2	2-531	N		MS	auf dem Keller et al., 2010
284	cathepsin D	2-531	P		MS	Impens et al., 2010
284	cathepsin E	2-531	P		MS	Impens et al., 2010
307	cathepsin D	2-531	P		MS	Impens et al., 2010
307	cathepsin E	2-531	P		MS	Impens et al., 2010
308	cathepsin E	2-531	P		MS	Impens et al., 2010
331	cathepsin E	2-531	P		MS	Impens et al., 2010
351	matrix metallopeptidase-2	2-531	N		MS	auf dem Keller et al., 2010
354	caspase-3	2-531	N		MS	Demon et al., 2009
354	caspase-7	2-531	N		MS	Demon et al., 2009
357	cathepsin D	2-531	P		MS	Impens et al., 2010
358	cathepsin E	2-531	P		MS	Impens et al., 2010
360	cathepsin E	2-531	P		MS	Impens et al., 2010
361	cathepsin D	2-531	P		MS	Impens et al., 2010
363	matrix metallopeptidase-2	2-531	N		MS	auf dem Keller et al., 2010
416	matrix metallopeptidase-2	2-531	N		MS	auf dem Keller et al., 2010
427	cathepsin E	2-531	P		MS	Impens et al., 2010
480	matrix metallopeptidase-2	2-531	N		MS	auf dem Keller et al., 2010