Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P49767

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
31	unknown peptidase	1-419	P	release of a signal peptide	NT	Zhang & Henzel, 2004
102	kallikrein-related peptidase 4	1-419	P		CS	Matsumura et al., 2005
111	unknown peptidase	1-419	P		NT	<%Agarwal et al., 2012[]%>
227	furin	32-419	P			Siegfried et al., 2003
227	PCSK5 peptidase	32-419	P			Siegfried et al., 2003
227	PCSK7 peptidase	32-419	P			Siegfried et al., 2003