Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P41091

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-472	P		NT	<%Agarwal et al., 2012[]%>
8	elastase-2	1-17	N		MS	Schilling & Overall, 2008
17	trypsin 1	2-472	N		MS	Schilling & Overall, 2008
27	trypsin 1	2-472	N		MS	Schilling & Overall, 2008
272	meprin alpha subunit	269-285	N		MS	Becker-Pauly et al., 2011
272	meprin beta subunit	269-285	N		MS	Becker-Pauly et al., 2011
273	matrix metallopeptidase-2	260-285	N		MS	Schilling & Overall, 2008
285	trypsin 1	2-472	N		MS	Schilling & Overall, 2008
293	meprin alpha subunit	290-303	N		MS	Becker-Pauly et al., 2011
331	meprin alpha subunit	328-342	N		MS	Becker-Pauly et al., 2011
331	meprin beta subunit	328-342	N		MS	Becker-Pauly et al., 2011
331	LAST_MAM peptidase (Limulus-type)	328-342	N		MS	Becker-Pauly et al., 2011
426	trypsin 1	2-472	N		MS	Schilling & Overall, 2008
440	trypsin 1	2-472	N		MS	Schilling & Overall, 2008