Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P26339

,


Click here to display alignment and conservation of cleavage sites of this sequence with close homologues.  This will take a few moments.

Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site Peptidase Residue range Cleavage type Description Evidence Reference
18 unknown peptidase 1-463 P NT <%Agarwal et al., 2012[]%>
357 PCSK2 peptidase 19-463 P MS Pan et al., 2006
373 PCSK2 peptidase 19-463 P MS Pan et al., 2006
387 carboxypeptidase A4 374-388 P MS Tanco et al., 2010
391 PCSK2 peptidase 19-463 P MS Pan et al., 2006
401 carboxypeptidase A4 392-402 P MS Tanco et al., 2010
404 PCSK2 peptidase 19-463 P MS Pan et al., 2006