Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P21796

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	mitochondrial methionyl aminopeptidase	1-283	P	release of an initiating methionine	NT
99	meprin beta subunit	96-110	N		MS	Becker-Pauly et al., 2011
100	meprin beta subunit	97-110	N		MS	Becker-Pauly et al., 2011
100	glutamyl endopeptidase I	96-110	N		MS	Schilling & Overall, 2008
110	trypsin 1	2-283	N		MS	Schilling & Overall, 2008
125	cathepsin G	120-139	N		MS	Schilling & Overall, 2008
132	unknown peptidase	1-283	P		MS	Van Damme et al., 2005
139	trypsin 1	2-283	N		MS	Schilling & Overall, 2008
203	glutamyl endopeptidase I	201-218	N		MS	Schilling & Overall, 2008
218	trypsin 1	2-283	N		MS	Schilling & Overall, 2008
241	matrix metallopeptidase-2	236-256	N		MS	Schilling & Overall, 2008
256	trypsin 1	2-283	N		MS	Schilling & Overall, 2008
261	matrix metallopeptidase-2	230-280	N		MS	Schilling & Overall, 2008
280	glutamyl endopeptidase I	2-283	N		MS	Schilling & Overall, 2008