Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P20068

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
22	unknown peptidase	1-169	P	release of a signal peptide	NT	Bidard et al., 1993
141	PCSK1 peptidase	23-169	P			Rovère et al., 1996
141	PCSK2 peptidase	23-169	P			Rovère et al., 1996
147	cathepsin E	142-151	P	normal turnover		Kageyama et al., 1995
149	PCSK1 peptidase	23-169	P			Rovère et al., 1996
149	PCSK2 peptidase	23-169	P			Rovère et al., 1996
151	cathepsin E	142-165	P	normal turnover		Kageyama et al., 1995
162	cathepsin E	155-169	P	normal turnover		Kageyama et al., 1995
164	PCSK1 peptidase	23-169	P			Rovère et al., 1996
164	PCSK2 peptidase	23-169	P			Rovère et al., 1996