Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P17742

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site Peptidase Residue range Cleavage type Description Evidence Reference
1 unknown peptidase 1-164 P NT <%Agarwal et al., 2012[]%>
7 cathepsin D 2-164 P MS Impens et al., 2010
7 cathepsin E 2-164 P MS Impens et al., 2010
8 cathepsin D 2-164 P MS Impens et al., 2010
8 cathepsin E 2-164 P MS Impens et al., 2010
19 matrix metallopeptidase-2 2-164 N MS Kleifeld et al., 2010
22 cathepsin D 2-164 P MS Impens et al., 2010
22 cathepsin E 2-164 P MS Impens et al., 2010
23 matrix metallopeptidase-2 2-164 N MS auf dem Keller et al., 2010
24 cathepsin D 2-164 P MS Impens et al., 2010
24 cathepsin E 2-164 P MS Impens et al., 2010
25 cathepsin D 2-164 P MS Impens et al., 2010
26 cathepsin D 2-164 P MS Impens et al., 2010
35 matrix metallopeptidase-2 2-164 N MS Kleifeld et al., 2010
38 matrix metallopeptidase-2 2-164 N MS Kleifeld et al., 2010
38 carboxypeptidase A4 23-39 P ms Tanco et al., 2010
60 cathepsin D 2-164 P MS Impens et al., 2010
60 cathepsin E 2-164 P MS Impens et al., 2010
60 matrix metallopeptidase-2 2-164 N MS auf dem Keller et al., 2010
61 matrix metallopeptidase-2 2-164 N MS auf dem Keller et al., 2010
91 carboxypeptidase A4 84-92 P ms Tanco et al., 2010
99 carboxypeptidase A4 84-100 P ms Tanco et al., 2010
128 carboxypeptidase A4 118-129 P MS Tanco et al., 2010
129 cathepsin E 2-164 P MS Impens et al., 2010
130 matrix metallopeptidase-2 2-164 N MS auf dem Keller et al., 2010
131 matrix metallopeptidase-2 2-164 N MS auf dem Keller et al., 2010