Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P13497

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
22	unknown peptidase	1-986	P		NT	<%Agarwal et al., 2012[]%>
120	furin	23-986	P			Leighton & Kadler, 2003
120	PCSK2 peptidase	115-124	N		CS	Remacle et al., 2008
120	PCSK4 peptidase	115-124	N		CS	Remacle et al., 2008
120	PCSK6 peptidase	115-124	N		CS	Remacle et al., 2008
120	PCSK5 peptidase	115-124	N		CS	Remacle et al., 2008
120	PCSK7 peptidase	115-124	N		CS	Remacle et al., 2008
317	chymotrypsin A (cattle-type)	121-986	N			Sieron et al., 2000
431	chymotrypsin A (cattle-type)	121-986	N			Sieron et al., 2000
509	chymotrypsin A (cattle-type)	121-986	N			Sieron et al., 2000
733	chymotrypsin A (cattle-type)	121-986	N			Sieron et al., 2000