Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P12830

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
22	unknown peptidase	1-882	P		NT	<%Agarwal et al., 2012[]%>
154	kallikrein-related peptidase 4	1-882	P		CS	Matsumura et al., 2005
585	membrane-type matrix metallopeptidase-1	1-882	P			<%Ito et al., 2000[]%>
586	membrane-type matrix metallopeptidase-1	1-882	P			<%Ito et al., 2000[]%>
700	matrix metallopeptidase-7	1-882	P			<%Davies et al., 2001[]%>
731	presenilin 1	23-882	P	release of a bioactive peptide		Xia & Wolfe, 2003
750	unknown peptidase	1-882	P		NT	<%Agarwal et al., 2012[]%>