Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P10909

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
22	ADAMTS5 peptidase	23-449	P			Zhen et al., 2008
43	ADAMTS5 peptidase	23-449	P			Zhen et al., 2008
48	meprin beta subunit	23-449	N		MS	Becker-Pauly et al., 2011
49	meprin alpha subunit	23-449	N		MS	Becker-Pauly et al., 2011
58	matrix metallopeptidase-12	23-449	P	normal turnover		Zhen et al., 2008
73	matrix metallopeptidase-12	23-449	P	normal turnover		Zhen et al., 2008
214	ADAMTS4 peptidase	23-449	P			Zhen et al., 2008
226	ADAMTS4 peptidase	23-449	P			Zhen et al., 2008
227	unknown peptidase	1-449	P		NT	<%Agarwal et al., 2012[]%>
259	matrix metallopeptidase-3	23-449	P			Zhen et al., 2008
259	matrix metallopeptidase-12	23-449	P			Zhen et al., 2008
263	meprin beta subunit	23-449	N		MS	Becker-Pauly et al., 2011
266	matrix metallopeptidase-11	228-449	N			Kleifeld et al., 2010
273	matrix metallopeptidase-3	23-449	P			Zhen et al., 2008
273	matrix metallopeptidase-12	23-449	P			Zhen et al., 2008
431	meprin alpha subunit	23-449	N		MS	Becker-Pauly et al., 2011
431	meprin beta subunit	23-449	N		MS	Becker-Pauly et al., 2011
432	meprin alpha subunit	23-449	N		MS	Becker-Pauly et al., 2011
432	meprin beta subunit	23-449	N		MS	Becker-Pauly et al., 2011
432	ADAMTS4 peptidase	23-449	P			Zhen et al., 2008
441	ADAMTS4 peptidase	23-449	P			Zhen et al., 2008