Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P0A6N1

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	methionyl aminopeptidase 1 (Escherichia-type)	1-394	P	release of an initiating methionine	NT	Link et al., 1997
22	caspase-3	2-394	N		MS	Timmer et al., 2009
51	caspase-3	2-394	N		MS	Timmer et al., 2009
60	Lit peptidase	2-394	P			Kraal et al., 1999
81	caspase-3	2-394	N		MS	Timmer et al., 2009
100	caspase-3	2-394	N		MS	Timmer et al., 2009
191	glutamyl endopeptidase I	2-394	N		MS	Timmer et al., 2009
197	caspase-3	2-394	N		MS	Timmer et al., 2009