Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P09958

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
24	unknown peptidase	1-794	P		NT	<%Agarwal et al., 2012[]%>
70	furin	25-794	N
75	furin	70-79	N		CS	Remacle et al., 2008
75	PCSK2 peptidase	70-79	N		CS	Remacle et al., 2008
75	PCSK4 peptidase	70-79	N		CS	Remacle et al., 2008
75	PCSK6 peptidase	70-79	N		CS	Remacle et al., 2008
75	PCSK5 peptidase	70-79	N		CS	Remacle et al., 2008
75	PCSK7 peptidase	70-79	N		CS	Remacle et al., 2008
104	furin	25-794	N			Leduc et al., 1992
107	furin	25-794	P			Leduc et al., 1992
107	PCSK2 peptidase	102-111	N		CS	Remacle et al., 2008
107	PCSK4 peptidase	102-111	N		CS	Remacle et al., 2008
107	PCSK6 peptidase	102-111	N		CS	Remacle et al., 2008
107	PCSK5 peptidase	102-111	N		CS	Remacle et al., 2008
107	PCSK7 peptidase	102-111	N		CS	Remacle et al., 2008