Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P08865

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
1	unknown peptidase	1-295	P		NT	<%Agarwal et al., 2012[]%>
21	cathepsin B	18-33	N		MS	Biniossek et al., 2011
63	trypsin 1	2-295	N		MS	Schilling & Overall, 2008
80	trypsin 1	2-295	N		MS	Schilling & Overall, 2008
89	trypsin 1	2-295	N		MS	Schilling & Overall, 2008
102	trypsin 1	2-295	N		MS	Schilling & Overall, 2008
115	unknown peptidase	1-295	P		NT	<%Agarwal et al., 2012[]%>
117	trypsin 1	2-295	N		MS	Schilling & Overall, 2008
133	unknown peptidase	1-295	P		NT	<%Agarwal et al., 2012[]%>
143	LAST_MAM peptidase (Limulus-type)	140-155	N		MS	Becker-Pauly et al., 2011
144	elastase-2	136-155	N		MS	Schilling & Overall, 2008
155	trypsin 1	2-295	N		MS	Schilling & Overall, 2008
166	trypsin 1	2-295	N		MS	Schilling & Overall, 2008
191	meprin alpha subunit	2-295	N		MS	Becker-Pauly et al., 2011
205	trypsin 1	2-295	N		MS	Schilling & Overall, 2008
220	trypsin 1	2-295	N		MS	Schilling & Overall, 2008