Searches of the MEROPS database

Display Known Cleavages for a Protein

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Accession:

Sequence P07585

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
16	unknown peptidase	1-359	P		NT	<%Agarwal et al., 2012[]%>
30	matrix metallopeptidase-2	17-359	P		NT	Imai et al., 1997
30	matrix metallopeptidase-3	17-359	P		NT	Imai et al., 1997
30	matrix metallopeptidase-7	17-359	P		NT	Imai et al., 1997
30	procollagen C-peptidase	17-359	P			Scott et al., 2000
31	matrix metallopeptidase-7	17-359	P			Imai et al., 1997
74	ADAMTS5 peptidase	31-359	P			Zhen et al., 2008
85	ADAMTS5 peptidase	31-359	P			Zhen et al., 2008
176	matrix metallopeptidase-12	31-359	P	normal turnover		Zhen et al., 2008
187	matrix metallopeptidase-12	31-359	P	normal turnover		Zhen et al., 2008
240	matrix metallopeptidase-2	31-359	P	normal turnover		Imai et al., 1997
240	matrix metallopeptidase-3	31-359	P	normal turnover		Imai et al., 1997
240	matrix metallopeptidase-13	31-359	P	normal turnover		Montfort et al., 2006
273	matrix metallopeptidase-7	17-359	P	normal turnover		Imai et al., 1997