Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P07225

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
24	unknown peptidase	1-676	P		NT	<%Agarwal et al., 2012[]%>
41	kallikrein-related peptidase 4	1-676	P		CS	Matsumura et al., 2005
90	thrombin	42-676	P	normal turnover		Heeb & Griffin, 2002
101	coagulation factor Xa	42-676	P			Heeb & Griffin, 2002
101	ACC-C peptidase	42-676	P			Heeb & Griffin, 2002
111	thrombin	42-676	P			Heeb & Griffin, 2002