Searches of the MEROPS database

Display Known Cleavages for a Protein

Please enter a UniProt accession (eg P05067):

Accession:

Sequence P06756

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Peptide and protein substrates that are thought to be physiologically relevant are indicated by P. Peptide and protein substrates that are not physiologically relevant are indicated by N. How cleavage sites have been identified are indicated by the following evidence codes: NT = N-terminal sequencing, MS = mass spectroscopy, MU = mutation, CS = consensus sequence, LC = liquid chromatography. To see all annotated cleavages for a peptidase, click on the peptidase name.

Cleavage Site	Peptidase	Residue range	Cleavage type	Description	Evidence	Reference
30	unknown peptidase	1-1012	P	release of a signal peptide	NT	Cheresh et al., 1989
889	unknown peptidase	1-1048	P		NT	<%Agarwal et al., 2012[]%>
890	furin	885-894	N		CS	Remacle et al., 2008
890	PCSK2 peptidase	885-894	N		CS	Remacle et al., 2008
890	PCSK4 peptidase	885-894	N		CS	Remacle et al., 2008
890	PCSK6 peptidase	885-894	N		CS	Remacle et al., 2008
890	PCSK5 peptidase	885-894	N		CS	Remacle et al., 2008
890	PCSK7 peptidase	885-894	N		CS	Remacle et al., 2008
891	membrane-type matrix metallopeptidase-1	31-1048	P			Ratnikov et al., 2002